Fig.1. Color print of Aedes aegypti mosquito (Credit: Emil August Goeldi, 1905) |
On Monday, the Democratic Republic of the Congo (DRC) declared a yellow fever epidemic in three provinces, including the heavily populated capital of Kinshasa. The current outbreak has killed more than 300 people in Angola and depleted the world’s vaccine stockpile to protect people in Angola, DRC, and Uganda. Although the outbreak is largely confined to central Africa, scientists worry about its potential spread to Asia, where 2 billion people live in areas infested with the disease’s vector, the Aedes aegypti mosquito.
Public health officials do not yet know which factors led to this event becoming the deadliest yellow fever outbreak since 1971. Whether the virus became more virulent or it came in contact with new populations, the question of why now sits at the heart of every outbreak. To answer this question, scientists are teasing apart the genetic and environmental factors that make a disease tick.
Public health officials do not yet know which factors led to this event becoming the deadliest yellow fever outbreak since 1971. Whether the virus became more virulent or it came in contact with new populations, the question of why now sits at the heart of every outbreak. To answer this question, scientists are teasing apart the genetic and environmental factors that make a disease tick.